Zodiac Eclipse – The Tiger’s Eye

Zodiac Eclipse – The Tiger’s EyeCoffee was not the same. It tasted just as good, but she couldn’t feel it warm her once she swallowed and it coursed down her artificial oesophagus. Brasidas and Drusus were briefing those selected to fly down to Naxos in The Sun Dancer’s mess hall. The twenty pirates who had been picked sipped coffee and smoked sabketh whilst they listened to their leaders. Gertrude was sat far from the purple smoke, on a table with only Sarah Wellington for company.

“Naxos is in dark space,” Brasidas explained. “The Elthurians charted it immediately prior to their extinction, and when the plague came knowledge of its existence returned to obscurity.”

“You want us to go to a damned plague planet?” Nicephorus interrupted.

Brasidas glared at the crewman. “It’s not a plague planet. The Elthurians never established an outpost there. Ask another stupid question and I’ll have you serve a shift in engineering.”

The other crewmen laughed and slapped Nicephorus on the back. Brasidas’s words had provoked a scowl on Nicephorus’s face.

“What’s so bad about that?” Gertrude whispered to Sarah.

The blonde pirate raised an eyebrow. “You haven’t met Primus yet?” Continue reading

Third special submission window for 2015

SubmissionsSubmission status – Closed

This is the third of six special submission windows for 2015. One story from those submitted will be published on the date specified.

Write a story inspired by the specified theme and within the specified genre.

Theme – Exploration of a planet.

NASA’s New Horizons spacecraft will fly by Pluto and Charon in July 2015

Write a science fiction story about the exploration (manned or robotic) of a planet (other than Earth). Aliens are optional.

Genre – Science Fiction

Length – 1,500 (+/- 50) words excluding the title.

Payment – £45 GBP

Publication date – 8th July 2015

Submission Window – 2nd May 2015 to 20th May 2015

Please use the Chronicles discussion thread for any questions.

General submission guidelines and terms of publication apply unless specified otherwise. Please see the FAQ’s for commonly asked questions.

Why I Hate the Seaside by E.J. Tett

Why I Hate the Seaside by E.J. TettJay was laughing and waving to us as we watched from the beach, telling us how nice the water was and that we should go and join him.

That was the last we heard from him. I remember protesting as Kirsty pulled me to my feet. I remember the pair of us running towards the water.

And I remember Jay’s screams as something pulled him beneath the waves.

Read Why I Hate the Seaside

 

Why I Hate the Seaside

Why I Hate the SeasideJay was laughing and waving to us as we watched from the beach, telling us how nice the water was and that we should go and join him.

That was the last we heard from him. I remember protesting as Kirsty pulled me to my feet. I remember the pair of us running towards the water.

And I remember Jay’s screams as something pulled him beneath the waves.

That was ten years ago now. I was only nine. Kirsty was eleven and our brother was thirteen.

“Unlucky for some!”

“Don’t butt in. That’s not even funny. You wanted to know why I hate this place, I’m telling you.”

We’d always go to this same beach every summer; my aunt and uncle owned a chalet on the seafront so it was a cheap holiday for the family. I never liked swimming but Kirsty and Jay loved it. I preferred to sit on the beach and build sandcastles. Maybe eat an ice cream.

I remember that year we met some other kids, I remember what they looked like but for the life of me, I can’t remember their names.

“I’m going to get an ice cream, do you want one?”

“No! Finish the story. I’m here; nothing’s going to happen.”
Continue reading

Zodiac Eclipse – Negotiation

Zodiac Eclipse – NegotiationThe twenty hexapod robots, twin pulse cannons still trained on Gertrude, Brasidas and the others, began scuttling slowly towards the compound. The War Dogs shepherded the human pirates through the massive black gates. Gertrude was the last one inside, and the gates rumbled shut behind her.

“Lord Ump’gomptar will receive Captain Brasidas,” one of the War Dogs stated in a robotic voice. “The others shall remain here.”

The robot that had spoken turned around, a prolonged process on its six legs, and led the captain away at walking pace. The remaining mechanoids shuffled a little closer together to fill the gap it had left, and continued to surround Gertrude and the others.

“Is this the normal welcome you get?” she muttered to Drusus.

If he was concerned, the Murovian did a good job of hiding it. “More mechs than usual, and we’ve never had an escort down to the ground before. Something’s rattled the Ralgo.”

The interior of the compound was almost as sandy as the desert beyond the walls. Bleak and featureless grey stone boxes were the only buildings within the compound. They rose only a few storeys high, and, to her surprise, there were no more than half a dozen. The walls encompassed an area large enough to accommodate a town, but the lack of structures meant only a few hundred people could live there. Continue reading

Report on the Testing of PK563217M

Report on the Testing of PK563217M

Background

PK563217M is a highly selective ligand for the dopamine D7 receptor, Ki 4.2nM at the cloned human receptor. GTP gamma S binding establishes it as a full agonist. It has a clean profile of activity against other dopamine receptors (>500nM); the nearest activity is at D4 (230nM), and no significant interaction with serotinergic, adrenergic, noradrenergic, muscarinic, cholinergic or histamine receptors. The bioavailability of PK563217M is 27% in rat (half-life 5 hours) and 38% in dog (half-life 8 hours). No significant toxicological effects were observed during 28 days dosing in rat and dog at doses below 75mg/kg. PK563217M was formulated in a gel capsule with starch filler for first human dosing

Testing Protocol

Subjects were recruited from undergraduates of ****** University Medical School and were medically and psychologically profiled before dosing. Subjects were scheduled to receive 5mg capsules of PK563217M for 5 consecutive days, followed by 9 days washout and 2 x 5mg capsules for 5 consecutive days. The individual responses to the initial dosing are reported below.

Human Pharmacology

Samples were taken from the subjects at 30-minute intervals and indicate that PK563217M achieved peak plasma levels 1 hour post dosing with a mean half-life of 10 hours. Continue reading